Table 3 Grade ≥ 3 adverse events
Grade ≥ 3 adverse events | 2019 Royal Marsden % (n = 50) (%) | 2017 study (n = 28) (%) | 2013 GRID study (n = 132) (%) |
|---|---|---|---|
All grade ≥ 3 AEs | 23 (46) | 12 (42.9) | 81 (61.4) |
PPE | 9 (18) | 5 (17.9) | 26 (19.7) |
Fatigue | 7 (14) | 5 (17.9) | 3 (2.3) |
Hypertension | 4 (8) | 2 (7.1) | 31 (23.5) |
Hepatotoxicity | 1 (2) | 0 (0) | 1 (0.8) |
Diarrhoea | 1 (2) | 2 (7.1) | 7 (5.3) |
Arthralgia | 1 (2) | 0 (0) | 1 (1%) |