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  1. Case Report

    Primary Kaposi’s sarcoma of the nasal cavity: a case report and review of the literature

    Kaposi sarcoma is a neoplastic vascular disorder. It usually present on the skin of the upper and lower extremities, rarely in the mucosa of the head and neck. The most common sites reported are within the ora...

    Karima Mouden, Mouna Khmou, Saida Loughmari, Afaf Semmar, Hanan El Kacemi, Basma El Khannoussi, Tayeb Kebdani, Sanaa Elmajjaoui and Noureddine Benjaafar

    Clinical Sarcoma Research 2016 6:4

    Published on: 17 March 2016

  2. Meeting Report

    The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24–25, 2015. Workshop Report

    This report summarizes the results of the 3rd Joint ENCCA-WP7, EuroSarc, EEC, PROVABES, and EURAMOS European Bone Sarcoma Network Meeting, which was held at the Children’s Cancer Research Institute in Vienna, ...

    Leo Kager, Jeremy Whelan, Uta Dirksen, Bass Hassan, Jakob Anninga, Lindsey Bennister, Judith V. M. G. Bovée, Bernadette Brennan, Javier M. Broto, Laurence Brugières, Anne-Marie Cleton-Jansen, Christopher Copland, Aurélie Dutour, Franca Fagioli, Stefano Ferrari, Marta Fiocco…

    Clinical Sarcoma Research 2016 6:3

    Published on: 16 March 2016

  3. Case Report

    Metastatic mesenteric dedifferentiated leiomyosarcoma: a case report and a review of literature

    Abdominal leiomyosarcoma arising from the mesentery is a rare malignancy. It is an aggressive entity with an overall 5 year survival rate between 20 and 30 %. Surgical resection is the cornerstone of primary t...

    Mercy Varghese, Oyvind Bruland, Anne Marit Wiedswang, Ingvild Lobmaier, Bård Røsok, Robert S. Benjamin and Kirsten Sundby Hall

    Clinical Sarcoma Research 2016 6:2

    Published on: 24 February 2016

  4. Research

    Tumor volume is a better predictor of post-operative wound complications compared to tumor size in soft tissue sarcomas of the proximal lower extremity

    Wide local excision with or without radiation therapy (RT) and chemotherapy is widely accepted as appropriate management for soft tissue sarcomas (STS) of the extremity. Although survival and local control rat...

    Michael Ziegele, David M. King and Manpreet Bedi

    Clinical Sarcoma Research 2016 6:1

    Published on: 22 February 2016

  5. Case Report

    High-grade soft tissue sarcoma arising in a desmoid tumor: case report and review of the literature

    Desmoid tumors are rare benign monoclonal fibroblastic tumors. Their aggressiveness is local with no potential for metastasis or dedifferentiation. Here we report on a 61-year-old patient who presented a local...

    François Bertucci, Marjorie Faure, Maria-Rosa Ghigna, Bruno Chetaille, Jérôme Guiramand, Laurence Moureau-Zabotto, Anthony Sarran and Delphine Perrot

    Clinical Sarcoma Research 2015 5:25

    Published on: 30 November 2015

  6. Case Report

    Alveolar rhabdomyosarcoma confined to the bone marrow with no identifiable primary tumour using FDG-PET/CT

    Rhabdomyosarcoma (RMS), a malignant tumour of mesenchymal origin which can occur at various sites in the body, is one of the most common soft tissue sarcomas in both children and adolescents, but is rare in ad...

    Panagiotis Karagiannis, Nina Guth, Gabriela B. Thoennissen, Christina Bern, Jan Sperveslage, Ilske Oschlies, Carsten Bokemeyer, Wolfram Klapper, Eva Wardelmann and Nils H. Thoennissen

    Clinical Sarcoma Research 2015 5:24

    Published on: 19 November 2015

  7. Research

    High-grade focal areas in low-grade central osteosarcoma: high-grade or still low-grade osteosarcoma?

    High-grade foci (grade 3 according to Broder’s grading system) are sometimes detected in low-grade (grade 1 and 2) central osteosarcoma. The aim of this study was to retrospectively evaluate the clinical outco...

    Alberto Righi, Anna Paioli, Angelo Paolo Dei Tos, Marco Gambarotti, Emanuela Palmerini, Manuela Cesari, Emanuela Marchesi, Davide Maria Donati, Piero Picci and Stefano Ferrari

    Clinical Sarcoma Research 2015 5:23

    Published on: 29 October 2015

  8. Case Report

    Cytotoxic and targeted therapy for treatment of pseudomyogenic hemangioendothelioma

    Pseudomyogenic hemangioendothelioma (PMH) is a recently described, indolent vascular tumor that usually presents in the distal extremities. PMH typically has a multi-focal presentation and can involve several ...

    Jason Joseph, Wei-lien Wang, Madhavi Patnana, Naveen Ramesh, Robert Benjamin, Shreyaskumar Patel and Vinod Ravi

    Clinical Sarcoma Research 2015 5:22

    Published on: 19 October 2015

  9. Research

    Retroperitoneal solitary fibrous tumor: surgery as first line therapy

    Solitary fibrous tumors (SFT) of the retroperitoneum are rare spindle cell neoplasms, with a paucity of data on treatment outcomes. We hypothesized that surgical excision offered acceptable outcomes in SFTs.

    Rahul Rajeev, Mohit Patel, Thejus T. Jayakrishnan, Fabian M. Johnston, Meena Bedi, John Charlson and Kiran K. Turaga

    Clinical Sarcoma Research 2015 5:19

    Published on: 27 August 2015

  10. Research

    Older soft tissue sarcoma patients experience increased rates of venous thromboembolic events: a retrospective cohort study of SEER-Medicare data

    Venous thromboembolic co-morbidities can have a significant impact on treatment response, treatment options, quality of life, and ultimately, survival from cancer. There is a dearth of published information on...

    Sumitra Shantakumar, Alexandra Connelly-Frost, Monica G Kobayashi, Robert Allis and Li Li

    Clinical Sarcoma Research 2015 5:18

    Published on: 26 July 2015

  11. Research

    Perioperative chemotherapy in the treatment of osteosarcoma: a 26-year single institution review

    Chemotherapy in the multimodality treatment of osteosarcoma has improved survival. Reported outcomes on adult patients are limited. Poor necrosis rates post neoadjuvant chemotherapy (NAC) is considered an adve...

    G M O’Kane, K A Cadoo, E M Walsh, R Emerson, P Dervan, C O’Keane, B Hurson, G O’Toole, S Dudeney, E Kavanagh, S Eustace and D N Carney

    Clinical Sarcoma Research 2015 5:17

    Published on: 14 July 2015

  12. Research

    Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture

    In vitro expanded mesenchymal stromal cells (MSCs) are increasingly used as experimental cellular therapy. However, there have been concerns regarding the safety of their use, particularly with regard to possi...

    Emilie P Buddingh, S Eriaty N Ruslan, Christianne M A Reijnders, Karoly Szuhai, Marieke L Kuijjer, Helene Roelofs, Pancras C W Hogendoorn, R Maarten Egeler, Anne-Marie Cleton-Jansen and Arjan C Lankester

    Clinical Sarcoma Research 2015 5:16

    Published on: 23 June 2015

  13. Research

    A phase II trial to assess the activity of gemcitabine and docetaxel as first line chemotherapy treatment in patients with unresectable leiomyosarcoma

    Gemcitabine and docetaxel have been shown to be active in pre-treated relapsed leiomyosarcoma. This study investigated the combination as first line treatment in patients with unresectable locally advanced/met...

    Beatrice Seddon, Michelle Scurr, Robin L Jones, Zoe Wood, Cerys Propert-Lewis, Cyril Fisher, Adrienne Flanagan, Jonanthan Sunkersing, Roger A’Hern, Jeremy Whelan and Ian Judson

    Clinical Sarcoma Research 2015 5:13

    Published on: 16 May 2015

  14. Case Report

    Eight years tumor control with pazopanib for a metastatic resistant epithelioid hemangioendothelioma

    Epithelioid hemangioendothelioma is a rare connective tissue tumor of vascular origin. It is most commonly found in young to middle aged women, and its clinical behavior is remakably variable from an indolent ...

    Olivia Bally, Louis Tassy, Bertrand Richioud, Anne-Valérie Decouvelaere, Jean-Yves Blay and Olfa Derbel

    Clinical Sarcoma Research 2015 5:12

    Published on: 23 April 2015

  15. Short Report

    Do human tumor-associated viruses play a role in the development of synovial sarcoma?

    To date, the pathomechanism of soft tissue sarcomas such as synovial sarcoma remains unclear whereas even a viral etiology was suspected. Aim of this study was to analyze whether EBV, HHV-8 or HPV play a role ...

    Ulrich Lenze, Florian Pohlig, Heinrich Mühlhofer, Florian Lenze, Andreas Toepfer, Hans Rechl, Rainer Burgkart, Rüdiger von Eisenhart-Rothe and Melanie Straub

    Clinical Sarcoma Research 2015 5:11

    Published on: 15 April 2015

  16. Research

    Hormonal treatments in metastatic endometrial stromal sarcomas: the 10-year experience of the sarcoma unit of Royal Marsden Hospital

    Hormonal manipulation is sometimes recommended in the treatment of metastatic endometrial stromal sarcoma, but there are few data assessing the efficacy of endocrine therapies in this subtype of uterine sarcomas.

    Eirini Thanopoulou, Aleksandar Aleksic, Khin Thway, Komel Khabra and Ian Judson

    Clinical Sarcoma Research 2015 5:8

    Published on: 15 March 2015

  17. Case Report

    Response of conventional chondrosarcoma to gemcitabine alone: a case report

    Conventional skeletal chondrosarcoma is a bone neoplasm, which is poorly sensitive to anthracyclines-based chemotherapy. We report on an 18-month-long tumour response to gemcitabine as single agent in a young ...

    Salvatore Provenzano, Nadia Hindi, Carlo Morosi, Mara Ghilardi, Paola Collini, Paolo G Casali and Silvia Stacchiotti

    Clinical Sarcoma Research 2015 5:9

    Published on: 15 March 2015

  18. Research

    Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases

    Recently a few cases of synovial sarcoma (SS) of the abdominal viscera have been reported, raising awareness about the potential for confusion between this entity and KIT-negative gastrointestinal stromal tumo...

    Salvatore Romeo, Sabrina Rossi, Marthelena Acosta Marín, Fabio Canal, Marta Sbaraglia, Licia Laurino, Guido Mazzoleni, Maria Cristina Montesco, Laura Valori, Marta Campo Dell’Orto, Andrea Gianatti, Alexander Joseph Lazar and Angelo Paolo Dei Tos

    Clinical Sarcoma Research 2015 5:7

    Published on: 12 February 2015

  19. Review

    Solitary intraosseous schwannoma of the base and vault of the skull: a summary review of such unusual location

    Intra-osseous schwannoma is a rare mesenchymal tumor. Although, the head and neck region is one of the most common sites for schwannomas, its location at the skull bone is uncommon and accounted for less than ...

    Fadoua Rais, Naoual Benhmidou, Ghizlane Rais, Fadila Kouhen, Khadija Bellahamou, Hasna Loughlimi, Abdelhak Maghous, Sanae Elmejjaoui, Hanan Elkacemi, Tayeb Kebdani and Noureddine Benjaafar

    Clinical Sarcoma Research 2015 5:6

    Published on: 9 February 2015

  20. Research

    Pazopanib as first line treatment for solitary fibrous tumours: the Royal Marsden Hospital experience

    Solitary Fibrous Tumour (SFT) is a rare soft tissue neoplasm, described in several locations in the body. It is classified as intermediate malignant potential with low risk of metastasis and has a low tendency...

    Marco Maruzzo, Juan Martin-Liberal, Christina Messiou, Aisha Miah, Khin Thway, Rolyn Alvarado, Ian Judson and Charlotte Benson

    Clinical Sarcoma Research 2015 5:5

    Published on: 2 February 2015

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