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• Racial background [17]
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• A record of the anatomical bone involved by tumour.
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• Clinical features associated with the tumour, such as nature and duration of signs and symptoms, including the presence or absence of pain, swelling, deformity, and relation to a previous traumatic episode.
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• The presence or absence of a pre-existing or concomitant skeletal disease, history of familial syndrome or other relevant disease predisposing to tumour development.
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• Occupational or treatment (eg chemotherapy, radiation therapy) history that may predispose to bone malignancy.
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• The presence or absence of systemic features of disease.
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• Results of relevant laboratory investigations (see text).
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