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Table 5 BONE TUMOUR DIAGNOSIS: CLINICAL FEATURES

From: Guidelines for histopathological specimen examination and diagnostic reporting of primary bone tumours

• Age (date of birth) and sex of the patient.

• Racial background [17]

• A record of the anatomical bone involved by tumour.

• Clinical features associated with the tumour, such as nature and duration of signs and symptoms, including the presence or absence of pain, swelling, deformity, and relation to a previous traumatic episode.

• The presence or absence of a pre-existing or concomitant skeletal disease, history of familial syndrome or other relevant disease predisposing to tumour development.

• Occupational or treatment (eg chemotherapy, radiation therapy) history that may predispose to bone malignancy.

• The presence or absence of systemic features of disease.

• Results of relevant laboratory investigations (see text).