• The precise anatomical location of the lesion in the affected bone (ie epiphyseal, metaphyseal, diaphyseal, medullary, cortical, periosteal or extraosseous in location). |
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• The size of the lesion |
• The matrix composition of the lesion • The nature of the zone of transition or interface between the lesion and surrounding bone. • The pattern of bone destruction |
• The presence or absence of infiltration of medullary bone. |
• The presence or absence of cortical destruction and soft tissue involvement |
• The nature of the periosteal reaction |
• The presence of multiple lesions within bone |