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Table 1 Patient characteristics.

From: Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma

Characteristic

Resectable tumor No. (%)

Advanced disease No. (%)

Total No. (%)

P value

Total no. of patients

26

11

37

 

Sex

   

0.48

   Male

15 (57.7)

3 (27.3)

18 (48.6)

 

   Female

11 (42.3)

8 (72.7)

19 (51.4)

 

Race

   

0.35

   White

15 (57.7)

10 (90.9)

25 (67.6)

 

   Hispanic

6 (23.0)

1 (9.1)

7 (18.9)

 

   African American

4 (15.4)

0 (0)

4 (10.8)

 

   Asian

1 (3.8)

0 (0)

1 (2.7)

 

Age in years at the time of treatment, mean ± SD (range)

42.3 ± 12.8 (14-72)

43.8 ± 6.4 (37-55)

42.7 ± 11.4 (14-72)

0.87

Tumor size in cm, median (range)

14.9 (6-23.3)

   

Disease site

    

   Lower extremity

23 (88.5)

   

   Neck

1 (3.8)

   

   Retroperitoneum

1 (3.8)

   

   Perineum

1 (3.8)

   

Number of disease sites

    

Single site (abdominal cavity, bone a , heart, mediastinum)

 

5 (45.5)

  

2 sites b

 

5 (45.5)

  

3 sites c

 

1 (9.1)

  

Tumor side

    

   Left

15 (57.7)

   

   Right

11 (42.3)

   

Hypercellular round cell tumor

1 (3.8)

1 (9.1)

2 (5.4)

0.82

Chemotherapy

    

   Median no. of chemotherapy cycles, median (range)

6 (4-6)

6 (5-8)

6 (4-8)

0.02

   Intensified doxorubicin dose (90 mg/m2)

8 (30.7)

3 (27.2)

11 (33.3)

1.00

Surgery (R0 intent)

26 (100)

   

   Free margins

21 (80.8)

   

   Positive margins (R1)

5 (19.2)

   

Radiotherapy

    

   Before surgery

21 (80.8)

   

   After surgery

5 (19.2)

   
  1. aAll bony involvement is reported as a single site (involved bones: sternum and spine, orbit and rib).
  2. bInvoled sites: lung and sacrum, retroperitoneum and chest wall, sacrum/T5 and peritoneum, sacrum and buttock, mediastinum and tibia (local recurrence).
  3. cInvolved sites: Pelvis, lung and abdominal cavity implants.