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Table 5 Ongoing phase I or II trials in osteosarcoma (Assessed from www.ClinicalTrials.gov)

From: Comprehensive analysis of published phase I/II clinical trials between 1990-2010 in osteosarcoma and Ewing sarcoma confirms limited outcomes and need for translational investment

ClinicalTrials.gov Identifier Sponsors Title Status
NCT00102531 Transave Phase Ib/IIa non-randomised study of SLIT Cisplatin by inhalation in the treatment of patients with relapsed/progressive osteosarcoma metastatic to the lung Recruiting
NCT01002092 Shandong Simcere-Medgenn
Bio-pharmaceutical Co., Ltd
A randomized, controlled multicenter trial of Endostar combined with chemotherapy for treatment of osteosarcoma (phase II) Recruiting
NCT00889057 Italian Sarcoma Group Phase II, open label, non-randomized study of second or third line treatment with Sorafenib (BAY 43-9006) in patients affected by relapsed high-grade osteosarcoma Recruiting
NCT00752206
NCT00923286
Sarcoma Alliance for Research through Collaboration (SARC) A randomized, double-blinded, placebo-controlled, multi-institutional, phase II study of AZD0530, a selective Src kinase inhibitor, in patients with recurrent osteosarcoma localized to the lung Recruiting
NCT01005043 University of Heidelberg Phase I/II therapy non-randomised trial to determine the safety and efficacy of heavy ion radiotherapy in patients with osteosarcoma Not yet recruiting
NCT00902044 Baylor College of Medicine Administration of Her2 Chimeric antigen receptor expressing T Cells for subjects with advanced osteosarcoma (HEROS) (phase I) Not yet recruiting