The attitudes of people with sarcoma and their family towards genomics and incidental information arising from genetic research

Table 4 Beliefs about altering inherited risk by modifying lifestyle factors

		Beliefs about altering disease risk
		Bivariable analysis			Multivariable analysis
Variable	Category	OR	95% CI	p	Adj OR	95% CI	p
Participant	Proband	Ref	Ref	Ref	Ref	Ref	Ref
	Family member	0.91	0.71-1.17	0.47	0.98	0.74-1.30	0.85
	Spouse	1.19	0.84-1.70	0.33	1.29	0.90-1.84	0.17
Age at study	18 to 39 years	Ref	Ref	Ref	Ref	Ref	Ref
	40 to 60 years	0.93	0.70-1.24	0.64	0.95	0.72-1.27	0.75
	61 years and older	0.74	0.55-1.00	0.05	0.78	0.56-1.08	0.14
Gender	Female	Ref	Ref	Ref	Ref	Ref	Ref
	Male	1.61	1.28-2.04	<0.001	1.64	1.28-2.08	<0.001
Highest education	Primary School	Ref	Ref	Ref	Ref	Ref	Ref
	High School	1.29	0.92-1.81	0.13	1.21	0.84-1.73	0.30
	University/Vocational	1.46	1.11-1.94	0.01	1.39	1.01-1.91	0.04
Country of birth	Australia/NZ	Ref	Ref	Ref	Ref	Ref	Ref
	Other	1.15	0.88-1.51	0.32	1.15	0.83-1.59	0.41

Logistic regression analysis. 0 = Not possible to alter risk, 1 = Possible to alter risk.
Multivariable analysis adjusted for age, gender, education, COB, genetic beliefs.

ISSN: 2045-3329