Table 1 Demographic information and tumor characteristics of patients included in genotyping ancillary study
Overall sample | Sex stratified | Race stratified | |||
|---|---|---|---|---|---|
N = 279 | Male (n = 142) | Female (n = 137) | White (n = 229) | Other (n = 50) | |
Age: Median (range) | 58.0 (18 – 85) | 57.0 (18 – 85) | 58.0 (18 – 81) | 59.0 (18 – 85) | 53.0 (27 – 78) |
Sex: N (%) | |||||
Male | 142 (51) | --- | --- | --- | --- |
Female | 137 (49) | --- | --- | --- | --- |
Race: N (%) | |||||
White | 229 (82) | 122 (86) | 107 (78) | --- | --- |
Other | 50 (18) | 20 (14) | 30 (22) | --- | --- |
Tumor Size: Median (range) | 6.5 (3.0 – 37.0) | 6.0 (3.0 – 37.0) | 6.5 (3.0 – 28.0) | 6.5 (3.0 – 37.0) | 6.0 (3.1 – 30.0) |
Tumor Size: N(%) | |||||
<5 cm | 79 (28) | 41 (29) | 38 (28) | 65 (28) | 14 (28) |
5-10 cm | 146 (52) | 72 (51) | 74 (54) | 119 (52) | 27 (54) |
>10 cm | 54 (19) | 29 (20) | 25 (18) | 45 (20) | 9 (18) |
Mitotic Rate: Median (range) | 3 (0 – 351) | 3 (0 – 351) | 3 (0 – 207) | 3 (0 – 351) | 4.5 (0 – 81) |
Mitotic Rate: N(%) | |||||
<5 | 156 (60) | 77 (58) | 79 (63) | 132 (62) | 24 (50) |
≥5 | 104 (40) | 57 (42) | 47 (37) | 80 (38) | 24 (50) |
Missing | 19 | 8 | 11 | 17 | 2 |
Tumor Location: N(%) | |||||
Stomach | 182 (66) | 97 (69) | 85 (63) | 146 (64) | 36 (74) |
Small Intestine | 85 (31) | 39 (28) | 46 (34) | 77 (34) | 8 (16) |
Rectum | 2 (1) | 1 (1) | 1 (1) | 1 (0) | 1 (2) |
Other | 8 (3) | 4 (3) | 4 (3) | 4 (2) | 4 (8) |
Missing | 2 | 1 | 1 | 1 | 1 |
Mutation Type: N(%) | |||||
Exon 9 | 15 (5) | 9 (6) | 6 (4) | 15 (7) | 0 (0) |
Exon 11 | 195 (70) | 95 (67) | 100 (73) | 153 (67) | 42 (84) |
Exon 13 | 3 (1) | 0 (0) | 3 (2) | 2 (1) | 1 (2) |
Exon 14 | 1 (0) | 1 (1) | 0 (0) | 1 (0) | 0 (0) |
Exon 17 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
PDGFRA | 29 (10) | 21 (15) | 8 (6) | 25 (11) | 4 (8) |
Wild type | 36 (13) | 16 (11) | 20 (15) | 33 (14) | 3 (6) |
Exon 11 mutation type: N(%) | |||||
557-558 deletion | 66 (34) | 33 (35) | 33 (33) | 51 (33) | 15 (36) |
Other deletion | 45 (23) | 25 (26) | 20 (20) | 34 (22) | 11 (26) |
Insertion | 28 (14) | 14 (15) | 14 (14) | 23 (15) | 5 (12) |
Point Mutation | 56 (29) | 23 (24) | 33 (33) | 45 (29) | 11 (26) |
PDGFRA mutation type: N(%) | |||||
D842V | 12 (41) | 10 (48) | 2 (25) | 10 (40) | 2 (50) |
Other | 17 (59) | 11 (52) | 6 (75) | 15 (60) | 2 (50) |