Variables | No. of patients (%) |
---|---|
Treatment modality | Â |
Chemotherapy | 38 (93%) |
   - Neoadjuvant | 4 (10%) |
   - Adjuvant | 2 (5%) |
   - Palliative (including relapse after neoadjuvant/ adjuvant treatment) | 35 (85%) |
Radiotherapy | Â |
   - Radical | 2 (5%) |
   - Palliative | 4 (10%) |
Surgery and its indications | Â |
   - Diagnosis | 14 (34%) |
   - Resection/optimal debulking of primary tumour | 8 (20%) |
Chemotherapy | Â |
First-line | Â |
   - Vincristine + ifosfamide + doxorubicin + etoposide (VIDE) | 13 |
   - Ifosfamide + vincristine + actinomycin D + doxorubicin (IVADo) | 7 |
   - Cyclophosphamide or ifosfamide + etoposide | 4 |
   - Vincristine + doxorubicin + cyclophosphamide (VAC) or vincristine + ifosfamide + doxorubicin | 4 |
   - Bleomycin + etoposide + cisplatin | 2 |
   - Ifosfamide + doxorubicin | 2 |
   - Carboplatin + etoposide | 1 |
   - Carboplatin + paclitaxel | 1 |
   - Cisplatin + doxorubicin/paclitaxel + cisplatin + ifosfamide | 1 |
   - Doxorubicin | 1 |
   - Epirubicin + cisplatin + capecitabine | 1 |
   - Ifosfamide + carboplatin + etoposide | 1 |
   - Ifosfamide + vincristine + actinomycin D | 1 |
Subsequent-line (with chemotherapeutic agents) | Â |
   - Platinum + etoposide | 10 |
   - Etoposide | 5 |
   - Ifosfamide + etoposide | 5 |
   - Doxorubicin | 2 |
   - Ifosfamide + doxorubicin | 2 |
   - Cyclophosphamide + topotecan | 2 |
   - VAC | 2 |
   - Gemcitabine or irinotecan + temozolomide | 2 |
   - Albumin-bound paclitaxel | 1 |
   - Cisplatin + mitomycin C + irinotecan | 1 |
   - Doxorubicin + etoposide | 1 |
   - IVADo | 1 |
   - Liposomal doxorubicin | 1 |
   - VIDE | 1 |
Subsequent-line (with non-standard therapies) | Â |
   - Figitumumab | 2 |
   - Sirolimus + cyclophosphamide or liposomal doxorubicin | 2 |
   - Pazopanib +/− etoposide | 2 |
   - Sunitinib | 2 |
   - Axitinib | 1 |
   - Goserelin | 1 |
   - Interferon | 1 |
   - Semaxanib | 1 |
   - Sorafenib | 1 |