Figure 2From: Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinibPath and phospho-receptor tirosine kinase (phRTK) array evaluation of Patient 1. The phRTK array analysis showed PDGFRB and CSFR1 activation, as indicated in panel A by the red and blue arrows, respectively. Immunohistochemistry resulted positive for platelet-derived growth factor receptor beta (PDGFRB) and colony-stimulating-factor1-receptor (CSF1R) expression (panel B and C, respectively).Back to article page