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Table 2 Toxicity – number of patients/proportion out of all 20 patients

From: Regorafenib treatment for advanced, refractory gastrointestinal stromal tumor: a report of the UK managed access program

Toxicity

All grades

Grade 3-4

Fatigue

16 (80%)

1 (5%)

Hand-foot-syndrome

11 (55%)

3 (15%)

Hypertension

10 (50%)

3 (15%)

Diarrhoea

10 (50%)

-

Oral mucositis

8 (40%)

1 (5%)

Hoarseness

8 (40%)

-

Constipation

7 (35%)

-

Rash, maculopapular

6 (30%)

2 (10%)

Anorexia

5 (25%)

-

Nausea

4 (20%)

-

Hepatobiliary toxicity

2(10%)

1(5%)