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Table 3 Patient treatment details (n = 16)

From: Treatment of hormone positive uterine leiomyosarcoma with aromatase inhibitors

Variable - 1st line

n (%), median (range)

Initial management at diagnosis of ULMS

 

Surgical resection alone

3 (19%)

Surgical resection and BSO

13 (81%)

Number of prior chemotherapy regimens

 

0

12 (75%)

1

2 (12.5%)

2

2 (12.5%)

Prior exogenous estrogens

 

Tamoxifen

3 (19%) , 60 months

HRT

4 (25%), 48 months (24–96)

Prior pelvic radiotherapy

1 (6%)

Median interval between diagnosis (surgery) and letrozole initiation

37 months (2–308)

  1. ULMS, uterine leiomyosarcoma; BSO, bilateral salpingo-oophorectomy; HRT, hormonal replacement therapy.