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Figure 1 | Clinical Sarcoma Research

Figure 1

From: Primary Synovial Sarcoma (SS) of the digestive system: a molecular and clinicopathological study of fifteen cases

Figure 1

Digestive tract SS features: A- Neoplastic cells were involving gastric wall with focal extension to nearby perivisceral soft tissue and serosal ulceration (case 2, 12.5 X original magnification, HE staining). B- Most of the cases were composed of monomorphic spindle cells (case 9, 400 X original magnification, HE staining). C- Poorly differentiated SS featuring monomorphic round cells with elevated mitotic rate were encountered in 3 cases (case 4, 400 X original magnification, HE staining). D- Focal positivity for DOG1 staining was found in one case(Case 9, 400 X original magnification). E- Interphase FISH showed split a part of the two signal in most of the nuclei (case 9, original 1000X magnification). F- A fusion transcript SS18-SSX1 was amplified by Q-PCR (plot showing the amplification curves of SS18-SSX1, SS18-SSX2 and beta-microglobulin).

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