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Table 1 Patient, tumor, therapy and recurrence characteristics of PAS and SAS

From: Primary and secondary angiosarcomas: a comparative single-center analysis

Characteristic Primary angiosarcomas Secondary angiosarcomas p value
n % n %
Total number of patients 18 64.3 10 35.7  
 Male 13 72.2 2 20 0.0163
 Female 5 27.8 8 80
Age at initial diagnosis, median 52.9 years 64.2 years 0.1448
Primary tumor site      0.0012
 Superficial soft tissue or skin 4 22.2 0 0  
 Deep soft tissue or internal organs 12 66.7 2 20  
 Breast or chest wall 2 11.1 8 80  
At initial diagnosis      
 Localized disease 12 66.7 8 80 0.6692
 Metastatic disease 6 33.3 2 20
Primary therapy      
 Surgical resection      >0.95
  Yes 16 88.9 9 90  
  No 2 11.1 1 10  
 R-status      0.2421
  R0 8 50 8 88.9  
  R1 3 18.8 0 0  
  R2 1 6.2 0 0  
  Unknown 4 25 1 11.1  
 Radiotherapy      0.1282
  Yes 5 27.8 0 0  
  No 13 72.2 10 100  
 Chemotherapy and targeted therapy      0.3642
  Yes 6 33.3 1 10  
  No 12 66.7 9 90  
 Chemoradiotherapy      0.3571
  Yes 0 0 1 10  
  No 18 100 9 90  
Recurrence      0.2543
 Yes 8 44.4 7 70  
 No 10 55.6 3 30  
Local recurrence 5 27.8 5 50 0.4119
Recurrence therapy      
 Surgical resection      >0.95
  Yes 6 75 5 71.4  
  No 2 25 2 28.6  
 Radiotherapy      >0.95
  Yes 1 12.5 0 0  
  No 7 87.5 7 100  
 Chemotherapy and targeted therapy      0.3147
  Yes 3 37.5 5 71.4  
  No 5 62.5 2 82.6