Table 1 Patient, tumor, therapy and recurrence characteristics of PAS and SAS
From: Primary and secondary angiosarcomas: a comparative single-center analysis
Characteristic | Primary angiosarcomas | Secondary angiosarcomas | p value | ||
|---|---|---|---|---|---|
n | % | n | % | ||
Total number of patients | 18 | 64.3 | 10 | 35.7 | |
Male | 13 | 72.2 | 2 | 20 | 0.0163 |
Female | 5 | 27.8 | 8 | 80 | |
Age at initial diagnosis, median | 52.9 years | 64.2 years | 0.1448 | ||
Primary tumor site | 0.0012 | ||||
Superficial soft tissue or skin | 4 | 22.2 | 0 | 0 | |
Deep soft tissue or internal organs | 12 | 66.7 | 2 | 20 | |
Breast or chest wall | 2 | 11.1 | 8 | 80 | |
At initial diagnosis | |||||
Localized disease | 12 | 66.7 | 8 | 80 | 0.6692 |
Metastatic disease | 6 | 33.3 | 2 | 20 | |
Primary therapy | |||||
Surgical resection | >0.95 | ||||
Yes | 16 | 88.9 | 9 | 90 | |
No | 2 | 11.1 | 1 | 10 | |
R-status | 0.2421 | ||||
R0 | 8 | 50 | 8 | 88.9 | |
R1 | 3 | 18.8 | 0 | 0 | |
R2 | 1 | 6.2 | 0 | 0 | |
Unknown | 4 | 25 | 1 | 11.1 | |
Radiotherapy | 0.1282 | ||||
Yes | 5 | 27.8 | 0 | 0 | |
No | 13 | 72.2 | 10 | 100 | |
Chemotherapy and targeted therapy | 0.3642 | ||||
Yes | 6 | 33.3 | 1 | 10 | |
No | 12 | 66.7 | 9 | 90 | |
Chemoradiotherapy | 0.3571 | ||||
Yes | 0 | 0 | 1 | 10 | |
No | 18 | 100 | 9 | 90 | |
Recurrence | 0.2543 | ||||
Yes | 8 | 44.4 | 7 | 70 | |
No | 10 | 55.6 | 3 | 30 | |
Local recurrence | 5 | 27.8 | 5 | 50 | 0.4119 |
Recurrence therapy | |||||
Surgical resection | >0.95 | ||||
Yes | 6 | 75 | 5 | 71.4 | |
No | 2 | 25 | 2 | 28.6 | |
Radiotherapy | >0.95 | ||||
Yes | 1 | 12.5 | 0 | 0 | |
No | 7 | 87.5 | 7 | 100 | |
Chemotherapy and targeted therapy | 0.3147 | ||||
Yes | 3 | 37.5 | 5 | 71.4 | |
No | 5 | 62.5 | 2 | 82.6 | |