A phase II trial to assess the activity of gemcitabine and docetaxel as first line chemotherapy treatment in patients with unresectable leiomyosarcoma

Table 3 Phase II studies of gemcitabine and docetaxel in locally advanced/metastatic leiomyosarcoma

Study	N^a	uLMS^b	LMS^c	Line of treatment	Median PFS^d (months)	3 month PFR^e (%)	6 month PFR (%)
Hensley et al. [8]	34	✓	✓	1st and 2nd	5.6	–	47
Hensley et al. [6]	42	✓	–	1st	4.4	59.5	40.5
Hensley et al. [5]	48	✓	–	2nd	6.7+	73	52
Pautier et al. [7]	46	✓	✓	2nd	3.4–4.7^f	53–71^f	47–48^f
This study	44	✓	✓	1st	7.1	70.5	59.1

ISSN: 2045-3329