Retroperitoneal solitary fibrous tumor: surgery as first line therapy

Table 1 Baseline characteristics and therapies of solitary fibrous tumor (SFT) patients from National Cancer Database (NCDB) and systematic review

Characteristic	NCDB (51 pts)		Systematic review (24 pts)
Characteristic	Median (IQR)^a	Frequency N (%)	Median (IQR)^a	Frequency N (%)
(Age (years)	60 (49–72)		47.5 (39–66.5)
Gender
Male		30 (58.8)		14 (58.3)
Female		21 (41.2)		10 (41.7)
Tumor size (cm)	16 (11–21)		12 (7–17)
<10 cm		12 (23.5)		7 (29.2)
≥10 cm		35 (68.6)		11 (45.8)
Tumor grade
Well-differentiated		6 (11.76)
Moderately differentiated		6 (11.76)
Poorly differentiated		6 (11.76)
Undifferentiated/anaplastic		5 (9.8)
Distant metastasis at diagnosis		4 (9.09)
Surgery		47 (92.2)		22 (91.7)
Surgical margins^b
Negative (R0)		30 (63.8)
Microscopic positive (R1)		2 (4.3)
Gross positive (R2)		3 (6.4)
Unknown		12 (25.5)
Unplanned 30-day readmission^b		4 (8.5)
30-day mortality^b		1 (2.1)
Radiation therapy		16 (31.4)
Adjuvant		13 (25.5)
Neo-adjuvant		3 (5.8)
Chemotherapy		10 (19.6)		1 (4.2)
Adjuvant		5 (9.8)
Neo-adjuvant		3 (5.8)
Systemic		2 (3.9)
Combination therapy		4 (7.8)
Late recurrences				4 (16.7)
Follow-up (months)	45.2 (30.3–63.3)		54 (28–144)
Mortality at last follow-up		10 (19.6)		3 (12.5)

^a IQR inter-quartile range
^bPercentages are calculated on the number of patients who had surgery for the tumor

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