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Table 1 Patients characteristics according phenotype

From: Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study

Characteristic

Phenotype− (N = 80)

Phenotype+ (n = 12)

p value

Female

33 (41 %)

8 (66 %)

0.13

Mean age (SD)

60.7 (18.8)

65.1 (12.3)

0.20

Metastatic status

  

0.8

 1 site

61 (76 %)

10 (83 %)

 

 >1 site

19 (24 %)

2 (17 %)

 

Primary site

  

0.4

 Stomach

30 (37)

5 (42)

 

 Small bowel

33 (41)

2 (16)

 

 Other

17 (22)

5 (42)

 

KIT/PDGFR status

  

0.006

 KIT mutation

64 (79 %)

7 (58 %)

 

 PDGFR

2 (3 %)

3 (25 %)

 

 WT

14 (18 %)

2 (17 %)

 

ECOG PS

  

0.79

 0–1

72 (90 %)

11 (92 %)

 

 2

8 (10 %)

1 (8 %)

 

Liver metastasis

48 (60 %)

7 (58 %)

0.91

Surgery of primary

74 (92 %)

11 (92 %)

0.91

Disease free interval

 <24 months

20 (25 %)

4 (33 %)

0.5

 >24 months

60 (75 %)

8 (67 %)

 

 Mean LDH (SD)

332.1 (160.8)

482.4 (429.8)

0.39

 Mean leucocytes (SD)

7.1 (3)

8.1 (5.1)

0.56

 Mean albumin (SD)

40.9 (7.1)

39.6 (6.1)

0.62

  1. SD standard deviation