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Table 1 Patients characteristics according phenotype

From: Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study

Characteristic Phenotype− (N = 80) Phenotype+ (n = 12) p value
Female 33 (41 %) 8 (66 %) 0.13
Mean age (SD) 60.7 (18.8) 65.1 (12.3) 0.20
Metastatic status    0.8
 1 site 61 (76 %) 10 (83 %)  
 >1 site 19 (24 %) 2 (17 %)  
Primary site    0.4
 Stomach 30 (37) 5 (42)  
 Small bowel 33 (41) 2 (16)  
 Other 17 (22) 5 (42)  
KIT/PDGFR status    0.006
 KIT mutation 64 (79 %) 7 (58 %)  
 PDGFR 2 (3 %) 3 (25 %)  
 WT 14 (18 %) 2 (17 %)  
ECOG PS    0.79
 0–1 72 (90 %) 11 (92 %)  
 2 8 (10 %) 1 (8 %)  
Liver metastasis 48 (60 %) 7 (58 %) 0.91
Surgery of primary 74 (92 %) 11 (92 %) 0.91
Disease free interval
 <24 months 20 (25 %) 4 (33 %) 0.5
 >24 months 60 (75 %) 8 (67 %)  
 Mean LDH (SD) 332.1 (160.8) 482.4 (429.8) 0.39
 Mean leucocytes (SD) 7.1 (3) 8.1 (5.1) 0.56
 Mean albumin (SD) 40.9 (7.1) 39.6 (6.1) 0.62
  1. SD standard deviation