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Table 2 Cox proportional hazards regression for mortality in 819 patients with synovial sarcoma diagnosed between 2000 and 2010

From: Outcome and the effect of age and socioeconomic status in 1318 patients with synovial sarcoma in the English National Cancer Registry: 1985–2009

Variable

All patients

Children and adolescents

Adults

Hazard ratio (95 % CI)

Hazard ratio (95 % CI)

Hazard ratio (95 % CI)

Age category, years

 0–19

1.00

 20–29

1.39 (0.84–2.31)

 30–39

1.92 (1.20–3.07)**

 40–49

2.12 (1.32–3.43)**

 50–59

2.73 (1.68–4.45)***

 60–69

4.98 (3.08–8.05)***

 ≥ 70

8.48 (5.27–13.64)***

Sex

 Female

1.00

1.00

1.00

 Male

0.67 (0.54–0.84)***

0.95 (0.40–2.23)

0.70 (0.56–0.88)**

Primary site

 Extremity

1.00

1.00

1.00

 Other

2.25 (1.79–2.82)***

1.73 (0.68–4.36)

2.23 (1.76–2.82)***

Stage at diagnosisa

   

 Localised

1.00

1.00

1.00

 Metastatic

6.15 (4.75–7.95)***

42.4 (12.53–143.70)***

4.86 (3.74–6.33)***

Quintile of the income domain of the index of multiple deprivation 2010

 Least deprived

1.11 (0.78–1.59)

2.39 (0.47–12.19)

1.17 (0.81–1.68)

 2

1.34 (0.95–1.91)

1.68 (0.31–9.16)

1.33 (0.93–1.90)

 3

1.00

1.00

1.00

 4

1.18 (0.83–1.68)

0.61 (0.13–2.83)

1.22 (0.84–1.76)

Most deprived

1.48 (1.03–2.12)*

2.35 (0.54–10.16)

1.27 (0.88–1.84)

Time varying covariate

 Primary site

0.76 (0.64–0.91)**

0.73 (0.61–0.88)**

  1. * Statistically significant at p < 0.05
  2. ** Statistically significant at p < 0.01
  3. *** Statistically significant at p < 0.001
  4. aBased on 2010 data to allow further inclusion of metastases