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Fig. 1 | Clinical Sarcoma Research

Fig. 1

From: Clinical implications of repeated drug monitoring of imatinib in patients with metastatic gastrointestinal stromal tumour

Fig. 1

Boxplots showing imatinib mesylate (IM) trough levels (Cmin). Boxes indicate the median, the 25th and 75th percentile, and whiskers represent maximum and minimum values. Outliers are censored. Mean Cmin values ± standard deviations are indicated for each category. a IM Cmin levels categorised according to dose groups: <400 mg (n = 21), 400 mg (n = 69) and >400 mg (n = 6). b IM Cmin levels categorised according to gastric resection (n = 28) or not (n = 41). c IM Cmin levels categorised according to presence (n = 46) or absence (n = 23) of liver metastases. d IM Cmin levels categorised according to whether patients had experienced disease progression or not. For patients with disease progression (right panel), the left box represents the last plasma samples at stable disease and the box to the right represents the plasma samples at the time of progressive disease. For patients with stable disease (left panel), the left box represents the second last plasma samples and the box to the right represent the last plasma samples drawn

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