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Fig. 3 | Clinical Sarcoma Research

Fig. 3

From: IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas

Fig. 3

No difference in trimethylation of histone marks H3K4, H3K9 and H3K27 in central chondrosarcomas. Strong nuclear positivity for H3K4me3 (a), H3K9me3 (c) and H3K27me3 (e) in IDH wildtype central chondrosarcomas as well as central chondrosarcomas harboring an IDH mutation. Staining was scored as the sum of the intensity and the percentage of positive tumour cells (b, d, f). (Scores were rounded to zero decimal places and black bar indicates 50 µm)

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Clinical Sarcoma Research

ISSN: 2045-3329