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Table 1 Primary breast cancer characteristics and treatment in patients who developed RIAS

From: Radiation induced angiosarcoma of the breast: outcomes from a retrospective case series

  N = 49 (%)
Median age at RIAS diagnosis (range) 72 (51–93)
Primary breast cancer histology
 Infiltrating ductal carcinoma 25 (51.0)
 Infiltrating lobular carcinoma 3 (6.1)
 Ductal carcinoma in situ 1 (2.0)
 Unspecified 20 (40.8)
Surgery for primary breast cancer
 Wide local excision (WLE) 18 (36.7)
 WLE and axillary lymph node dissection 29 (59.2)
 Mastectomy 1 (2.0)
 Mastectomy and LD flap reconstruction 1 (2.0)
Adjuvant therapies
 Chemotherapy 10 (20.4)
 Endocrine therapy 36 (73.5)
 Trastuzumab 3 (6.1)
Radiation dose (Gy) (range)
 Primary median 50 (40–54)
 Boost median 12.5 (10–16)
  1. LD latissimus dorsi