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Table 2 Univariate and multivariate Cox regressional analyses for prognostic factors of distant metastases-free survival in patients with localised resectable RIAS

From: Radiation induced angiosarcoma of the breast: outcomes from a retrospective case series

Variable

Univariate

Multivariate

HR (95% CI)

p value

HR (95% CI)

p value

Age (years)

 <70

Reference

*

*

 ≥70

1.06 (0.98–1.15)

0.146

*

*

Positive margins

 No

Reference

*

*

 Yes

4.20 (1.12–15.67)

0.033

*

*

Tumour size (cm)

 <5

Reference

Reference

 ≥5

5.70 (1.18–27.50)

0.030

5.70 (1.18–27.50)

0.030

Treatment

 Surgery

Reference

*

*

 Surgery + chemotherapy

2.08 (0.46–9.51)

0.344

*

*

  1. *Not included in model generated by forward stepwise combination