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Table 4 Frequency of use of specific medications included in ‘Other’ category for LOT1-LOT3

From: A retrospective cohort study of treatment patterns among patients with metastatic soft tissue sarcoma in the US

  Frequency Percent (%)
LOT 1 regimen
 Carboplatin, paclitaxel 29 5.2
 Paclitaxel 28 5.0
 Carboplatin 18 3.2
 Temozolomide 14 2.5
 Bevacizumab 12 2.2
 Cyclophosphamide, doxorubicin, vincristine 9 1.6
 Sunitinib 8 1.4
 Docetaxel 8 1.4
 Etoposide 7 1.3
 Ifosfamide 7 1.3
 Etoposide, ifosfamide 6 1.1
 Carboplatin, docetaxel 6 1.1
 Irinotecan, temozolomide 5 0.9
 Sorafenib 5 0.9
 Gemcitabine, paclitaxel 4 0.7
 Carboplatin, etoposide 4 0.7
 Cyclophosphamide 4 0.7
 Dacarbazine 4 0.7
 Docetaxel, doxorubicin, gemcitabine 4 0.7
 Bevacizumab, temozolomide 3 0.5
 Bevacizumab, carboplatin, paclitaxel 3 0.5
 Vincristine 3 0.5
 Vinorelbine 3 0.5
 Carboplatin, gemcitabine 3 0.5
 Cyclophosphamide, dactinomycin, vincristine 3 0.5
 Cyclophosphamide, doxorubicin, etoposide, ifosfamide, vincristine 3 0.5
 Dacarbazine, doxorubicin 3 0.5
 Eribulin 3 0.5
 Gemcitabine, vinorelbine 2 0.4
 Irinotecan 2 0.4
 Irinotecan, temozolomide, vincristine 2 0.4
 Carboplatin, irinotecan 2 0.4
 Cyclophosphamide, etoposide 2 0.4
 Cyclophosphamide, vinorelbine 2 0.4
 Cyclophosphamide, dacarbazine, doxorubicin 2 0.4
 Cyclophosphamide, doxorubicin, irinotecan, vincristine 2 0.4
 Docetaxel, gemcitabine, pazopanib 2 0.4
 Doxorubicin, gemcitabine 2 0.4
 Doxorubicin, pazopanib 2 0.4
 Etoposide, ifosfamide, methotrexate 1 0.2
 Gemcitabine, ifosfamide 1 0.2
 Gemcitabine, sunitinib 1 0.2
 Ifosfamide, paclitaxel 1 0.2
 Methotrexate 1 0.2
 Pazopanib, sorafenib 1 0.2
 Bevacizumab, irinotecan 1 0.2
 Bevacizumab, irinotecan, temozolomide, vincristine 1 0.2
 Bevacizumab, paclitaxel 1 0.2
 Bevacizumab, docetaxel 1 0.2
 Bevacizumab, doxorubicin 1 0.2
 Temozolomide, topotecan, vincristine 1 0.2
 Carboplatin, etoposide, irinotecan 1 0.2
 Carboplatin, gemcitabine, paclitaxel 1 0.2
 Carboplatin, methotrexate, paclitaxel 1 0.2
 Carboplatin, epirubicin, paclitaxel 1 0.2
 Cyclophosphamide, dacarbazine, doxorubicin, vincristine 1 0.2
 Cyclophosphamide, doxorubicin 1 0.2
 Cyclophosphamide, doxorubicin, etoposide, vincristine 1 0.2
 Cyclophosphamide, doxorubicin, paclitaxel 1 0.2
 Dacarbazine, gemcitabine 1 0.2
 Dacarbazine, pazopanib 1 0.2
 Dacarbazine, doxorubicin, gemcitabine 1 0.2
 Dacarbazine, doxorubicin, ifosfamide 1 0.2
 Dacarbazine, doxorubicin, methotrexate 1 0.2
 Docetaxel, paclitaxel 1 0.2
 Docetaxel, doxorubicin, gemcitabine, ifosfamide 1 0.2
 Doxorubicin, gemcitabine, vinorelbine 1 0.2
 Doxorubicin, ifosfamide, pazopanib 1 0.2
 Doxorubicin, ifosfamide, vincristine 1 0.2
LOT 2 regimen
 Methotrexate 7 3.1
 Paclitaxel 7 3.1
 Carboplatin, paclitaxel 7 3.1
 Doxorubicin, ifosfamide 5 2.2
 Gemcitabine, paclitaxel 4 1.7
 Ifosfamide 4 1.7
 Sorafenib 4 1.7
 Vinorelbine 4 1.7
 Dacarbazine, doxorubicin 4 1.7
 Docetaxel 4 1.7
 Bevacizumab 3 1.3
 Carboplatin 3 1.3
 Dacarbazine 3 1.3
 Etoposide 2 0.9
 Bevacizumab, paclitaxel 2 0.9
 Bevacizumab, temozolomide 2 0.9
 Bevacizumab, docetaxel, gemcitabine 2 0.9
 Carboplatin, gemcitabine 2 0.9
 Doxorubicin, gemcitabine 2 0.9
 Eribulin 2 0.9
 Etoposide, ifosfamide 1 0.4
 Etoposide, ifosfamide, irinotecan, vincristine 1 0.4
 Gemcitabine, irinotecan 1 0.4
 Gemcitabine, pazopanib 1 0.4
 Gemcitabine, vinorelbine 1 0.4
 Irinotecan, temozolomide 1 0.4
 Irinotecan, temozolomide, vincristine 1 0.4
 Paclitaxel, pazopanib 1 0.4
 Pazopanib, sunitinib 1 0.4
 Sunitinib 1 0.4
 Bevacizumab, dacarbazine 1 0.4
 Bevacizumab, doxorubicin 1 0.4
 Topotecan 1 0.4
 Carboplatin, methotrexate, paclitaxel 1 0.4
 Cyclophosphamide, etoposide 1 0.4
 Cyclophosphamide, methotrexate 1 0.4
 Cyclophosphamide, temozolomide, topotecan 1 0.4
 Cyclophosphamide, topotecan 1 0.4
 Cyclophosphamide, vincristine 1 0.4
 Cyclophosphamide, dacarbazine, doxorubicin 1 0.4
 Cyclophosphamide, dacarbazine, doxorubicin, vincristine 1 0.4
 Cyclophosphamide, docetaxel 1 0.4
 Cyclophosphamide, doxorubicin, etoposide, ifosfamide 1 0.4
 Cyclophosphamide, doxorubicin, etoposide, ifosfamide, vincristine 1 0.4
 Cyclophosphamide, doxorubicin, vincristine 1 0.4
 Dacarbazine, gemcitabine 1 0.4
 Dacarbazine, ifosfamide 1 0.4
 Dacarbazine, doxorubicin, ifosfamide 1 0.4
 Docetaxel, gemcitabine, paclitaxel 1 0.4
 Docetaxel, gemcitabine, pazopanib 1 0.4
 Docetaxel, doxorubicin, gemcitabine 1 0.4
 Doxorubicin, gemcitabine, vinorelbine 1 0.4
 Doxorubicin, paclitaxel 1 0.4
 Doxorubicin, pazopanib 1 0.4
LOT 3 regimen
 Vinorelbine 4 4.5
 Gemcitabine 3 3.4
 Paclitaxel 2 2.3
 Cyclophosphamide, dactinomycin, vincristine 2 2.3
 Cyclophosphamide, doxorubicin, vincristine 2 2.3
 Docetaxel 2 2.3
 Etoposide, ifosfamide 1 1.1
 Etoposide, ifosfamide, irinotecan 1 1.1
 Gemcitabine, irinotecan 1 1.1
 Gemcitabine, methotrexate 1 1.1
 Ifosfamide 1 1.1
 Irinotecan, temozolomide 1 1.1
 Irinotecan, vincristine 1 1.1
 Sorafenib 1 1.1
 Bevacizumab, gemcitabine, paclitaxel 1 1.1
 Bevacizumab, cyclophosphamide, sorafenib 1 1.1
 Carboplatin 1 1.1
 Topotecan 1 1.1
 Cyclophosphamide, topotecan 1 1.1
 Cyclophosphamide, doxorubicin 1 1.1
 Cyclophosphamide, doxorubicin, irinotecan, vincristine 1 1.1
 Dacarbazine 1 1.1
 Dacarbazine, pazopanib 1 1.1
 Dacarbazine, vinorelbine 1 1.1
 Dacarbazine, doxorubicin 1 1.1