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Fig. 3 | Clinical Sarcoma Research

Fig. 3

From: Giant cell tumour of the distal radius/ulna: response to pre-operative treatment with short-term denosumab

Fig. 3

Patient 3: pre denosumab, a frontal plain radiograph demonstrates a Campanacci grade 2 distal ulnar GCTB with mild expansion and cortical thinning. b Axial T2-weighted fat saturated and c axial T1-weighted MR images confirm an expansile heterogeneous predominantly high T2- and low to isointense T1-weighted distal ulnar lesion (U ulnar, R radius). Post denosumab at 2 months, d frontal plain radiograph shows marginal sclerosis and internal matrix sclerosis, with mild modeling deformity of the ulnar articular surface (black arrow). e Axial T2-weighted fat saturated and f axial T1-weighted MR images show definition of cortical margins with the formation of marginal sclerosis seen as peripheral low T1 and T2-W signal (white arrows). The tumour matrix is more heterogeneous with areas of low T2-W signal reflecting internal matrix consolidation (R radius)

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Clinical Sarcoma Research

ISSN: 2045-3329