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Fig. 4 | Clinical Sarcoma Research

Fig. 4

From: Giant cell tumour of the distal radius/ulna: response to pre-operative treatment with short-term denosumab

Fig. 4

Patient 4: pre denosumab, a frontal plain radiograph demonstrates a lytic expansile Campanacci grade 2 distal radial GCTB with cortical thinning. b Coronal STIR MR image shows the lesion returns heterogeneous predominantly high STIR MR signal. c Fused PET/CT image illustrates marked FDG uptake with a standardized uptake value (SUV) of 17 (arrow). Post denosumab at 2 months, d coronal STIR MR image shows increased heterogeneity of MR signal with areas of low STIR signal reflecting matrix osteosclerosis (white arrows). e Fused PET/CT image confirms a significant decrease in FDG uptake with an SUV of 4.8 and the formation of marginal sclerosis (red arrows)

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Clinical Sarcoma Research

ISSN: 2045-3329