Skip to main content
Fig. 5 | Clinical Sarcoma Research

Fig. 5

From: Giant cell tumour of the distal radius/ulna: response to pre-operative treatment with short-term denosumab

Fig. 5

Patient 5: pre denosumab, a frontal plain radiograph illustrates a distal radial GCTB with moderate expansion and cortical thinning. A breach of the radial styloid articular surface (arrow) with soft tissue extending into the carpal joint was confirmed on MR imaging and this lesion was graded as Campanacci grade 3. b Fused PET/CT image confirms marked metabolic activity with an increased SUV of 19.5 (arrow). Post denosumab at 2 months, c frontal plain radiograph demonstrates an increase in size of the lesion despite marginal sclerosis with reconstitution of the radial articular surface (arrow) and quite marked intralesional matrix consolidation. d Fused PET/CT image confirms reduced activity of the lesion with a significant decrease in the SUV to 4.5 (arrow). Post surgical, e frontal plain radiograph 2 months post surgery shows tumour recurrence with rapid growth, progressive bone destruction and extrusion of cement (arrow)

Back to article page