Fig. 4
From: Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour
Histological analysis of the proximal tibial lesion shows primary pleomorphic liposarcoma of bone. a The tumor infiltrates cancellous bone and is composed of numerous lipoblasts and large pleomorphic cells, which have vacuolated cytoplasm and atypical nuclei. b Lipoblasts and brown fat-like cells are seen within the tumour. Immunohistochemistry shows the tumor cells express FABP4/aP2 (c) and UCP1 (d)