Table 1 Reported cases of primary liposarcoma of bone
From: Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour
Authors (reference) | Age/sex | Site | Subtype | Treatment | Metastasis | Outcome (comment) |
|---|---|---|---|---|---|---|
Fender [12] | 23/F | Fibula? | Unknown | Decompression | Intracranial | Alive, 22 months follow-up (primary uncertain) |
Barnard [13] | 30/F | Humerus | Unknown | Amputation | Lung | Died after 2 months |
Rehbock et al. [14] | 56/F 60/M | Femur Iliac bone | Unknown Unknown | Stabilisation and radiation – | Bone, lymph nodes – | Died after 14 months (case not convincing) Died after 2 weeks (case not convincing) |
Duffy et al. [15] | 49/M | Femur | Unknown | Amputation, radiation | – | Alive, 60 months follow-up |
Dawson et al. [3] | 28/F | Femur | Unknown | Amputation | Lung | Died after 11 months |
Retz [16] | 40/M | Tibia | Unknown | Amputation | – | Alive 24 months follow-up |
Johnson et al. [17] | 25/M 46/M | Humerus Humerus | Unknown Unknown | Amputation – | Lung Lung | Died after 26 months Died after 18 months |
Catto et al. [2] | 16/F | Tibia | Unknown | Amputation | Lung | Alive, 9 months follow-up |
Goldman et al. [18] | 33/M | Ulna | Unknown | Amputation | – | Alive, 5 months follow-up |
Ross et al. [19] | 15/M | Fibula | Unknown | Resection, radiation | Lung | Died after 5 months |
Schwartz et al. [20] | 49/M | Tibia | Unknown | Amputation | – | Alive, 7 months follow-up |
Larsson et al. [21] | 52/F | Femur | Unknown | Radiation | Lung | Died after 5 months |
Schneider et al. [22] | 69/M | Fibula | Unknown | Amputation | – | Unknown, 24 months follow-up |
Pardo-Mindan et al. [23] | 39/M | Humerus | Unknown | Unknown | Unknown | Unknown |
Cremer et al. [24] | 58/F 37/F | Femur Ilium | Unknown Unknown | Amputation Radiation, methotrexate, cordotomy | Lung Cerebral | Progression after 2,5 years with pulmonary metastasis Died after 3 years of cerebral metastasis |
Downey et al. [25] | 15/F | Ischium Ilium | Unknown | Hemi-pelvectomy | Lung | Died after 2 months of pneumothorax, Pleomorphic liposarcoma with osteosarcomatous foci |
Addison et al. [4] | 19/M | Humerus | Unknown | Amputation, radiation, chemotherapy | Lung | Died after 10 months |
Kenan et al. [26] | 57/M | Scapula | Myxoid | Curettage | – | Alive, 36 months follow up |
Seo et al. [27] | 69/M | Temporal bone | Well-differentiated | Resection | – | Alive, 24 months follow-up |
Macmull et al. [28] | 26/M | Femur | Well-differentiated | 2 cycles of neoadjuvant MAP, resection, adjuvant 4 cycles ifosfamide & etoposide. | – | Alive, 16 months follow-up |
Zhang et al. [29] | 26/M | Femur | De-differentiated | Wide resection | – | Alive, 12 months follow-up |
Torok et al. [30] | 34/M | Femur | Pleomorphic | Wide resection, radiation, chemotherapy | Lung | Died after 16 months, cause unknown |
Hamlat et al. [31] | 45/F | Thoracic spine | Pleomorphic | Laminectomy T7-T8 and radiotherapy | After 13 months lung and rib | 19 months follow-up, gradual deterioration of disease |
Torigoe et al. [32] | 38/F | Humerus | Pleomorphic | Wide resection with endoprosthesis replacement. Initial high-dose ifosfamide without effect, followed by cisplatin and doxorubicin | Liver | Died after 8 months of disease and liver failure |
Lmejjati [33] | 45/M | Lumbar spine | Pleomorphic | Emergency decompression at L4/L5 and radiotherapy (45 Gy) | None | Died after 3 months of deterioration from disease |
Rasalkar [34] | 13/M | Femur | Pleomorphic | Neoadjuvant MAP 2 cycles (methotrexate, adriamycin/cisplatin), Surgery, Adjuvant 1 cycle MAP and further chemotherapy with combinations of ifosfamide/etoposide and adriamycin/cisplatin | Lung | No recurrence of local disease and complete response at 13 months follow-up |