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Table 4 Predicted actionable therapeutics for patient 1

From: The use of whole exome sequencing and murine patient derived xenografts as a method of chemosensitivity testing in sarcoma

Drug Targets hit Potential targets P value (hypergeometric test)
Letrozole 1 5 < 0.001
Fludarabine 1 6 0.001
Sunitinib 1 9 0.001
Gemcitabine 1 11 0.002
Imatinib 1 10 0.002
Clofarabine 1 12 0.002
Regorafenib 1 18 0.005
Cytarabine 1 18 0.005
Doxorubicin 1 104 0.133
Cisplatin
Methotrexate
Ifosfamide
  1. Diagnosis was of osteosarcoma. Therapeutics that the patient had received are highlighted in italics