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Table 3 Association between the choice of local modality treatment and specified patient characteristics

From: Survival is influenced by approaches to local treatment of Ewing sarcoma within an international randomised controlled trial: analysis of EICESS-92

  Number of patients (percentage), excluding missing data
CCLG GPOH
N None RT alone Surgery alone RT and surgery N None RT alone Surgery alone RT and surgery
Disease
 Localised 150 9 (6) 53 (35) 59 (39) 29 (19) 315 3 (1) 55 (17) 63 (20) 194 (62)
 Metastatic 56 9 (16) 27 (48) 11 (20) 9 (16) 101 4 (4) 30 (30) 8 (8) 59 (58)
 Localised extremity disease 91 5 (5) 18 (20) 46 (50) 22 (24) 155 1 (1) 8 (5) 44 (28) 102 (66)
 Localised pelvic disease 31 0 24 (77) 6 (19) 1 (3) 79 1 (1) 27 (36) 7 (9) 39 (53)
Primary site
 Central axis 84 9 (11) 52 (62) 14 (17) 9 (11) 226 4 (2) 73 (32) 22 (10) 127 (56)
 Extremity 115 7 (6) 28 (24) 54 (47) 26 (23) 189 3 (2) 11 (6) 48 (25) 127 (67)
Volume (ml)
 < 100 57 5 (9) 19 (33) 27 (47) 6 (10) 111 3 (3) 26 (23) 16 (14) 66 (59)
 ≥ 100 146 13 (9) 61 (42) 40 (27) 32 (22) 292 4 (1) 54 (18) 52 (18) 182 (62)
Age (years)
 0–9 34 0 10 (29) 22 (65) 2 (6) 92 1 (1) 18 (20) 22 (24) 51 (55)
 10–14 74 5 (7) 32 (43) 24 (32) 13 (18) 118 0 30 (25) 11 (9) 77 (65)
 15–19 56 5 (9) 25 (45) 13 (23) 13 (23) 111 3 (3) 21 (19) 21 (19) 66 (59)
 20–35 43 8 (19) 14 (33) 11 (26) 10 (23) 97 3 (3) 16 (16) 17 (18) 61 (63)
  1. Chi square tests were used to examine the association between each factor and choice of local therapy, excluding those who received no local treatment (‘None’ in the table)
  2. CCLG: disease (p = 0.04); primary site (p < 0.001); volume (p = 0.01); age (p = 0.01)
  3. GPOH: disease (p = 0.002); primary site (p < 0.001); volume (p = 0.44); age (p = 0.12)
  4. N total number of patients RT radiotherapy