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Table 3 Association between the choice of local modality treatment and specified patient characteristics

From: Survival is influenced by approaches to local treatment of Ewing sarcoma within an international randomised controlled trial: analysis of EICESS-92

 

Number of patients (percentage), excluding missing data

CCLG

GPOH

N

None

RT alone

Surgery alone

RT and surgery

N

None

RT alone

Surgery alone

RT and surgery

Disease

 Localised

150

9 (6)

53 (35)

59 (39)

29 (19)

315

3 (1)

55 (17)

63 (20)

194 (62)

 Metastatic

56

9 (16)

27 (48)

11 (20)

9 (16)

101

4 (4)

30 (30)

8 (8)

59 (58)

 Localised extremity disease

91

5 (5)

18 (20)

46 (50)

22 (24)

155

1 (1)

8 (5)

44 (28)

102 (66)

 Localised pelvic disease

31

0

24 (77)

6 (19)

1 (3)

79

1 (1)

27 (36)

7 (9)

39 (53)

Primary site

 Central axis

84

9 (11)

52 (62)

14 (17)

9 (11)

226

4 (2)

73 (32)

22 (10)

127 (56)

 Extremity

115

7 (6)

28 (24)

54 (47)

26 (23)

189

3 (2)

11 (6)

48 (25)

127 (67)

Volume (ml)

 < 100

57

5 (9)

19 (33)

27 (47)

6 (10)

111

3 (3)

26 (23)

16 (14)

66 (59)

 ≥ 100

146

13 (9)

61 (42)

40 (27)

32 (22)

292

4 (1)

54 (18)

52 (18)

182 (62)

Age (years)

 0–9

34

0

10 (29)

22 (65)

2 (6)

92

1 (1)

18 (20)

22 (24)

51 (55)

 10–14

74

5 (7)

32 (43)

24 (32)

13 (18)

118

0

30 (25)

11 (9)

77 (65)

 15–19

56

5 (9)

25 (45)

13 (23)

13 (23)

111

3 (3)

21 (19)

21 (19)

66 (59)

 20–35

43

8 (19)

14 (33)

11 (26)

10 (23)

97

3 (3)

16 (16)

17 (18)

61 (63)

  1. Chi square tests were used to examine the association between each factor and choice of local therapy, excluding those who received no local treatment (‘None’ in the table)
  2. CCLG: disease (p = 0.04); primary site (p < 0.001); volume (p = 0.01); age (p = 0.01)
  3. GPOH: disease (p = 0.002); primary site (p < 0.001); volume (p = 0.44); age (p = 0.12)
  4. N total number of patients RT radiotherapy