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Fig. 4 | Clinical Sarcoma Research

Fig. 4

From: Retrospective audit of 957 consecutive 18F-FDG PET–CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma

Fig. 4

Distribution of the highest SUVmax values from each of 957 18F-FDG PET–CT scans within each sarcoma diagnostic sub-type in the primary lesion and following relapse (re-staging after primary treatment). High-grade sarcoma can have a propensity to relapse after primary (baseline) treatment (e.g. after surgery, radiotherapy and chemotherapy). The figure shows a comparison of the distribution of the highest SUVmax values per scan within subtypes, where there were also SUVmax values at relapse. The mean and 95% confidence intervals show non-significant differences (Non-parametric Mann–Whitney), but are suggestive of potential selection for higher-grade clones (higher SUVmax and altered confidence interval range) in relapse

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