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Table 2 Number of PET–CTs in which ‘added value’ was detected compared to conventional imaging (MRI/CT) according to sarcoma subtype

From: Retrospective audit of 957 consecutive 18F-FDG PET–CT scans compared to CT and MRI in 493 patients with different histological subtypes of bone and soft tissue sarcoma

Sarcoma pathological diagnosis

Percentage of PET–CT with added value

Number of PET–CT with added value over MRI/CT

Staging

Restaging

Treatment response

Undifferentiated pleomorphica

13.3% (22/166)

6

11

5

Angiosarcomab

9% (1/11)

1

0

0

Leiomyosarcoma

18% (30/166)

7

14

9

Rhabdomyosarcoma

24.6% (13/53)

3

2

8

Myxofibrosarcoma

26.7% (8/30)

0

5

3

Epithelioid sarcoma

13% (3/23)

1

2

0

Osteosarcoma

23.5% (23/98)

6

9

8

Clear cell sarcoma

12.5% (1/8)

1

0

0

Ewing sarcoma/DSRCT

27.5% (33/120)

7

12

14

Synovial sarcoma

13.6% (6/44)

3

2

1

De-differentiated liposarcoma

8.3% (3/36)

1

1

1

Solitary fibrous tumour

28% (7/25)

0

5

2

Chondrosarcoma grade 2/3

24.4% (11/45)

3

5

3

Myxoid/round cell liposarcoma

11.1% (4/36)

2

1

1

Alveolar soft part sarcoma

25% (1/4)

1

0

0

MPNST

41.6% (27/65)

14

9

4

Low grade soft tissue sarcoma

0% (0/17)

0

0

0

Chondrosarcoma grade 1

0% (0/10)

0

0

0

Total

21% (193/930)

56

78

59

  1. DSRCT desmoplastic small round cell sarcoma, MPNST malignant peripheral nerve sheath tumour, includes low-grade
  2. aIncludes high grade ‘spindle cell sarcoma’
  3. bIncludes ‘high grade epitheloid haemangioendothelioma’