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Fig. 4 | Clinical Sarcoma Research

Fig. 4

From: Reversible rituximab-induced rectal Kaposi’s sarcoma misdiagnosed as ulcerative colitis in a patient with HIV-negative follicular lymphoma

Fig. 4

Pathological aspect of the rectal Kaposi’s sarcoma. a Microscopic aspect of the biopsy of rectal ulceration: the rectal mucosa is infiltrated by an ill-defined cellular fasciculated to diffuse proliferation (HES ×10). b Microscopic aspect showing spindle cells with little to moderate nuclear atypia surround vascular clefts. Few mitoses are noted. Lymphocytes and plasma cells are admixed (HES ×40). c IHC with ERG antibody: the lining cells of vascular structures and spindle cells express the ERG endothelial marker (×20). d IHC with HHV8 antibody: see the nuclear positive immunostaining of spindle tumor cells (×40)

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