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Fig. 4 | Clinical Sarcoma Research

Fig. 4

From: Low-grade central fibroblastic osteosarcoma may be differentiated from its mimicker desmoplastic fibroma by genetic analysis

Fig. 4

Histology, karyotype and CDK4 expression in DF-LGOS. a Histology showing a fibroblastic tumor with permeative invasive growth (H&E, original magnification × 100). As such, the histology of DF-LGCOS resembles that of DF, shown in Fig. 2a. b DF-LGOS karyotype: 47~49,XX,del(13)(q12q32),+1~2r,+1~2mar,1dmin[cp17]/46,XX[2]. c Diffuse nuclear expression of CDK4 in cell nuclei of DF-LGCOS (original magnification × 200)

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