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Fig. 2 | Clinical Sarcoma Research

Fig. 2

From: Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs)

Fig. 2

KIT mutant GISTs have enrichment for KEGG cell cycle pathway (p = 0.0007) and spliceosome pathway (p = 0.0008) using STRING v10 clustering of significantly somatic mutated genes (p < 0.003). The left cluster represents the cell cycle genes CDC27, CUL1, TP53, RB1 and closely related mutated genes. The cluster on the right represents genes involved in spliceosome regulation, SF3A2, U2AF2, RBMX and other closely related genes

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Clinical Sarcoma Research

ISSN: 2045-3329