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Fig. 1 | Clinical Sarcoma Research

Fig. 1

From: Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype

Fig. 1

DNA-methylation profiling in atypical fibroxanthomas, pleomorphic dermal sarcomas and histologic mimics. Unsupervised hierarchical clustering (a) and t-Distributed Stochastic Neighbor Embedding (t-SNE) analysis (b) of DNA-methylation data from atypical fibroxanthomas (AFX), pleomorphic dermal sarcomas (PDS) and histologic mimics shows a close epigenetic relation to cutaneous squamous cell carcinomas (cSCC). This AFX/PDS/SCC methylation cluster clearly separated from the methylation clusters of other diagnostic mimics

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