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Table 1 Patients and disease characteristics in the entire population and according to adjuvant regimen

From: Anthracycline-based and gemcitabine-based chemotherapy in the adjuvant setting for stage I uterine leiomyosarcoma: a retrospective analysis at two reference centers

Characteristic Total (N = 109) G based (N = 43) A based (N = 66) P*
N (%) N (%) N (%)
Center 0.16
 INT 78 (72) 34 (79) 44 (67)
 IEO 31 (28) 9 (21) 22 (33)
Age 0.59
 Median 50 49 52
 IQR 43–57 43–56 44–59
Stage 0.59
 IA 20 (19) 7 (17) 13 (21)
 IB 83 (81) 35 (83) 48 (79)
 NA 6 1 5
Mitotic index 0.37
 Median 21 25 16
 IQR 12–34 14–34 12–33
 NA 55 16 39
Surgery 0.53
 LPT 90 (88) 34 (85) 56 (90)
 LPS 12 (12) 6 (15) 6 (10)
 NA 7 3 4
Morcellation 0.04
 No 52 (72) 15 (58) 37 (80)
 Yes 20 (28) 11 (42) 9 (20)
 NA 37 17 20
Oophorectomy 0.19
 No 27 (27) 13 (34) 14 (22)
 Yes 74 (73) 25 (66) 49 (78)
 NA 8 5 3
RT 0.05
 No 98 (90) 42 (98) 56 (85)
 Yes 11 (10) 1 (2) 10 (15)
  1. *Chi-square test, Fisher exact test or Mann-Whitney U test as appropriate
  2. INT Fondazione IRCCS Istituto Nazionale dei Tumori of Milan, IEO European Institute of Oncology, IQR interquartile range, G gemcitabine, A anthracycline, RT radiotherapy