Table 1 Bohan and Peter’s proposed diagnostic criteria for dermatomyositis
From: Paraneoplastic dermatomyositis associated with metastatic leiomyosarcoma of unknown primary
Criterion |
|---|
I Symmetrical proximal muscle weakness ± dysphagia or respiratory muscle involvement |
II Increase of skeletal muscle enzymes; creatine kinase, aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase |
III Abnormal EMG characteristic of myopathy |
IV Abnormal muscle biopsy |
V Typical cutaneous features (e.g. Gottron’s sign, heliotrope rash with periorbital oedema) |
Definite diagnosis: Criterion V and at least 3 of criteria I–IV Probable diagnosis: Criterion V and 2 of criteria I–IV Possible diagnosis: Criterion V and 1 of criteria I–IV |