Fig. 3
From: Simultaneous diagnosis of liver PEComa in a family with known Li–Fraumeni syndrome: a case report
a, b Pathological anatomy samples of hematoxylin–eosin staining (H&E 1.6×). A heterogeneous neoplastic lesion of 15 mm of mesenchymal lineage, partially encapsulated and circumscribed by hepatic parenchyma. c Cells have medium size, are polygonal, with well-defined cell borders, alternating clear cytoplasm and granular eosinophilic (PAS + granules). The cells have markedly pleomorphic nuclei with irregular contours and vesicular chromatin and visible nucleoli (H&E 20×). d Cell proliferation rate determined using KI67 is less than 5% by immunohistochemistry (IHC 4×). e, f IHC staining is positive for HMB45 (e) and focally positive for Melan-A (f) (IHC 20×)