The role of prognostic nutritional index in the management of pulmonary sarcomatoid carcinoma

Table 3 Uni and multivariable survival analysis for various potential prognostic factors of overall and recurrence-free survival in PSC patients with PNI more than 49.4

OS	Univariate analysis		Multivariate analysis			Univariate analysis		Multivariate analysis
OS	P value	X²	HR	95% CI	P value	P value	X²	HR	95% CI	P value
Age <= 60 vs. > 60	0.585	0.298				0.564	0.333
Sex Male vs. Female	0.897	0.017				0.949	0.004
Smoking history Yes vs. No	0.963	0.002				0.942	0.005
Alcohol abuse Yes vs. No	0.551	0.356				0.623	0.242
Tumor size > 5 vs. <= 5 cm	0.008	7.045	1.311	0.442-3.886	0.625	0.012	6.373	1.770	0.585–5.349	0.312
Tumor stage T3–4 vs. T1–2	0.062	3.496				0.091	2.860
Tumor location Peripheral vs. Central	0.194	1.687				0.157	2.001
Nodal metastasis Positive vs. Negative	< 0.001	14.076	1.164	0.451–3.004	0.753	< 0.001	27.165	3.328	1.105–10.022	0.033
Pathological stage IIb–IIIc vs. Ia–IIa	< 0.001	15.921	1.658	0.981–2.805	0.059	<0.001	17.590	1.230	0.723–2.095	0.445
Treatment modality	0.001	11.621			0.035	0.005	7.783			0.487
S + CT/S			0.288	0.095–0.874	0.028			0.649	0.248–1.700	0.379
S + CT + Targeted therapy/S			0.148	0.030–0.726	0.019			0.407	0.86–1.923	0.257

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