Table 2 Sensitivity and specificity values derived from the ROC curve
From: Accurate 3-gene-signature for early diagnosis of liposarcoma progression
Discovery cohort | |||||||
|---|---|---|---|---|---|---|---|
ALT/WDLPS (N) | DDLPS (N) | AUC | Sens | Spec | Cut off value (dCt) | ||
GLUT4 | 8 | 3 | 1 | 1 | 1 | 10.99 | |
LIPE | 8 | 3 | 1 | 1 | 1 | 7.06 | |
ATGL | 8 | 3 | 1 | 1 | 1 | 5.87 | |
PLIN1 | 8 | 3 | 1 | 1 | 1 | 6.22 | |
SCD1 | 8 | 3 | 1 | 1 | 1 | 6.87 | |
Validation cohort | |||||||
|---|---|---|---|---|---|---|---|
ALT/WDLPS (N) | DDLPS (N)a | AUC | Sens | Spec | Correct WDLPS | Correct DDLPS | |
GLUT4 | 9 | 17 | 0.912 | 0.824 | 1 | 9 of 9 | 14 of 17 |
LIPE | 9 | 17 | 1 | 1 | 1 | 9 of 9 | 17 of 17 |
ATGL | 9 | 17 | 0.944 | 1 | 0.889 | 8 of 9 | 17 of 17 |
PLIN1 | 9 | 17 | 0.941 | 0.882 | 1 | 9 of 9 | 15 of 17 |
SCD1 | 9 | 17 | 0.824 | 0.647 | 1 | 9 of 9 | 11 of 17 |