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Table 5 Immunohistochemical staining of 175 FFPE samples of chondrosarcoma patients

From: Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo

 

ESR1

aromatase

AR*

Enchondroma

2/2

100%

3/3

100%

0/2

0%

Central CS

34/42

81%

38/44

86%

6/41

15%

grade I

11/15

73%

13/15

87%

1/13

8%

grade II

14/16

88%

15/17

88%

3/16

19%

grade III

9/11

82%

10/12

83%

2/12

17%

Osteochondroma

5/8

63%

6/8

75%

1/7

14%

Peripheral CS

21/26

81%

25/27

93%

4/28

14%

grade I

9/11

82%

11/12

92%

2/12

17%

grade II

12/13

92%

12/13

92%

1/13

8%

grade III

1/3

33%

3/3

100%

1/3

33%

Dedifferentiated CS

      

well differentiated component

18/25

72%

31/32

97%

1/27

4%

dedifferentiated component

30/35

86%

34/38

89%

2/37

5%

Clear cell CS

15/22

69%

15/22

69%

0/22

0%

Mesenchymal CS

      

small cell component

15/23

65%

12/23

52%

1/23

4%

cartilaginous areas

5/15

33%

10/13

77%

0/12

0%

  1. * In positive samples only few strongly positive cells were observed.