Skip to main content

Table 2 Pediatric sarcoma study descriptions

From: The Epidemiology of Sarcoma

Location & time

Author

N Cases

N Controls/Cohort

Risk factors examined

Pooled USA, UK, Sweden, Spain, Italy, Germanya 1945–2001 [39]

Mirabello et al. (2011)

OS 1501

1,501,000^

Height at diagnosis, birth weight

Austrailia and Californiab 1978–1996 [40]

Valery et al. (2005)

ES 138

574

Hernias

USA-multiple locations (CA, MN, NY, TX, WA) 1980–2004 [41–44]

Spector et al. (2009), Von Behren et al. (2010), Ognjanovic et al. (2009), Johnson et al (2009)

MBT 573 & STS 1067, MBT 550 & STS 1054, RS 583, MBT 511 & STS 1000

57966, 57966, 57966, 57966

Birth weight, birth order, parental age, gestational age, and other birth characateristics

Meta-analysis USA & Canadac 1980–2002 [40]

Valery et al. (2005)

ES 357

745

Hernias

Cohort Connecticut, USA 1936–1979 [45]

Tucker et al. (1987)

MBT 64

9,170

Radiotherapy (treatment of primary childhood cancers)

Case–control Ontario, Canada 1964–1988 [46]

Finkelstein et al. (1996)

MBT 238

432

Radium in drinking water

North Carolina, United States 1967–1976 [47]

Grufferman et al. (1982)

RS 33

99

Parental smoking habits, maternal age, maternal antibiotic use, and vaccination history

Northern England 1968–2000 [48]

Pearce et al. (2007)

MBT 245 & STS 320

29,520

Paternal occupational exposure to electro-magnetic fields

USA-multiple locations 1972-? [47]

Winn et al. (1992)

ES 208

395

Parental smoking habits, hernias, and parental occupational factors

USA 1972–1997 [49]

Grufferman et al. (1993)

RS 322

322

Parental cocaine and marijuana use

Los Angeles, USA 1972–1981 [50]

Operskalski et al. (1987)

OS 64

124

Birth length, gestational age and height at diagnosis

New York State, USA 1978–1988 [51]

Gelberg et al. (1997)

OS 130

130

Birth weight, birth height, and pubertal growth factors

United Kingdom 1980–1983 [52, 53]

Hartley et al. (1988), Hartley et al. (1988)

MBT 30 & STS 43, MBT 30 & STS 43

146, 146

Birth weight, pregnancy conditions, antibiotic use after birth

Ontario, Canada 1980–1988 [54]

Hum et al. (1998)

MBT 152

713

Parental occupations

USA & Canada 1983–1987 [55]

Buckley et al. (1998)

OS 152 & ES 153

305

Birth weight, birth height, and pubertal growth factors

United Kingdom 1991–1996 [56]

Smith et al. (2009)

MBT & STS 251

6,337

Birth weight and gender

Austrailia 1991–1996 [57, 58]

Valery et al. (2003), Valery et al. (2002)

ES 106, ES 106

344, 344

Parental occupation, hernias, and pubertal growth factors

USA-multIple locations 1992–1995 [59]

Bassin et al. (2006)

139

280

Fluoride levels in drinking water

Germany 1992–1997 [60, 61]

Schuz et al. (2007), Shuz et al. (1999)

MBT 97 & STS 137, MBT 97 & STS 137

2057, 2588

Birth weight, family size, maternal age, gestational age, paternal smoking, birth weight for gestational age, and other birth characateristics

USA-multiple locations 1994–2000 [62]

Troisi et al. (2006)

OS 158

141

Birth weight, birth length, birth order, height and weight at diagnosis, and other pubertal growth factors

Case-series USA-multiple locations 1972–1978 [63]

Pendergrass et al. (1984)

ES 291

N/A

Adolescence stature: height and weight

United Kingdom 1978–1997 [64]

Cotterill et al. (2004)

MBT 720

N/A

Adolescent height, stature, and growth factors

  1. STS = Soft tissue sarcoma, MBT = Malignant bone tumor, KS = Kaposi's sarcoma, OS = Osteosarcoma, ES = Ewing's sarcoma, CS = Chondrosarcoma, RS = Rhabdomyosarcoma.
  2. ^2000 U.S. National Center for Health Statistics Simulated Controls.
  3. Already referenced studies included in pooled/meta analyses: a[41, 62, 64]b[57]c[54, 65].