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Table 2 Pediatric sarcoma study descriptions

From: The Epidemiology of Sarcoma

Location & time Author N Cases N Controls/Cohort Risk factors examined
Pooled USA, UK, Sweden, Spain, Italy, Germanya 1945–2001 [39] Mirabello et al. (2011) OS 1501 1,501,000^ Height at diagnosis, birth weight
Austrailia and Californiab 1978–1996 [40] Valery et al. (2005) ES 138 574 Hernias
USA-multiple locations (CA, MN, NY, TX, WA) 1980–2004 [4144] Spector et al. (2009), Von Behren et al. (2010), Ognjanovic et al. (2009), Johnson et al (2009) MBT 573 & STS 1067, MBT 550 & STS 1054, RS 583, MBT 511 & STS 1000 57966, 57966, 57966, 57966 Birth weight, birth order, parental age, gestational age, and other birth characateristics
Meta-analysis USA & Canadac 1980–2002 [40] Valery et al. (2005) ES 357 745 Hernias
Cohort Connecticut, USA 1936–1979 [45] Tucker et al. (1987) MBT 64 9,170 Radiotherapy (treatment of primary childhood cancers)
Case–control Ontario, Canada 1964–1988 [46] Finkelstein et al. (1996) MBT 238 432 Radium in drinking water
North Carolina, United States 1967–1976 [47] Grufferman et al. (1982) RS 33 99 Parental smoking habits, maternal age, maternal antibiotic use, and vaccination history
Northern England 1968–2000 [48] Pearce et al. (2007) MBT 245 & STS 320 29,520 Paternal occupational exposure to electro-magnetic fields
USA-multiple locations 1972-? [47] Winn et al. (1992) ES 208 395 Parental smoking habits, hernias, and parental occupational factors
USA 1972–1997 [49] Grufferman et al. (1993) RS 322 322 Parental cocaine and marijuana use
Los Angeles, USA 1972–1981 [50] Operskalski et al. (1987) OS 64 124 Birth length, gestational age and height at diagnosis
New York State, USA 1978–1988 [51] Gelberg et al. (1997) OS 130 130 Birth weight, birth height, and pubertal growth factors
United Kingdom 1980–1983 [52, 53] Hartley et al. (1988), Hartley et al. (1988) MBT 30 & STS 43, MBT 30 & STS 43 146, 146 Birth weight, pregnancy conditions, antibiotic use after birth
Ontario, Canada 1980–1988 [54] Hum et al. (1998) MBT 152 713 Parental occupations
USA & Canada 1983–1987 [55] Buckley et al. (1998) OS 152 & ES 153 305 Birth weight, birth height, and pubertal growth factors
United Kingdom 1991–1996 [56] Smith et al. (2009) MBT & STS 251 6,337 Birth weight and gender
Austrailia 1991–1996 [57, 58] Valery et al. (2003), Valery et al. (2002) ES 106, ES 106 344, 344 Parental occupation, hernias, and pubertal growth factors
USA-multIple locations 1992–1995 [59] Bassin et al. (2006) 139 280 Fluoride levels in drinking water
Germany 1992–1997 [60, 61] Schuz et al. (2007), Shuz et al. (1999) MBT 97 & STS 137, MBT 97 & STS 137 2057, 2588 Birth weight, family size, maternal age, gestational age, paternal smoking, birth weight for gestational age, and other birth characateristics
USA-multiple locations 1994–2000 [62] Troisi et al. (2006) OS 158 141 Birth weight, birth length, birth order, height and weight at diagnosis, and other pubertal growth factors
Case-series USA-multiple locations 1972–1978 [63] Pendergrass et al. (1984) ES 291 N/A Adolescence stature: height and weight
United Kingdom 1978–1997 [64] Cotterill et al. (2004) MBT 720 N/A Adolescent height, stature, and growth factors
  1. STS = Soft tissue sarcoma, MBT = Malignant bone tumor, KS = Kaposi's sarcoma, OS = Osteosarcoma, ES = Ewing's sarcoma, CS = Chondrosarcoma, RS = Rhabdomyosarcoma.
  2. ^2000 U.S. National Center for Health Statistics Simulated Controls.
  3. Already referenced studies included in pooled/meta analyses: a[41, 62, 64]b[57]c[54, 65].