Advertisement
Table 2 Pediatric sarcoma study descriptions
| Location & time | Author | N Cases | N Controls/Cohort | Risk factors examined |
|---|---|---|---|---|
| Pooled USA, UK, Sweden, Spain, Italy, Germanya 1945–2001 [39] | Mirabello et al. (2011) | OS 1501 | 1,501,000^ | Height at diagnosis, birth weight |
| Austrailia and Californiab 1978–1996 [40] | Valery et al. (2005) | ES 138 | 574 | Hernias |
| USA-multiple locations (CA, MN, NY, TX, WA) 1980–2004 [41–44] | Spector et al. (2009), Von Behren et al. (2010), Ognjanovic et al. (2009), Johnson et al (2009) | MBT 573 & STS 1067, MBT 550 & STS 1054, RS 583, MBT 511 & STS 1000 | 57966, 57966, 57966, 57966 | Birth weight, birth order, parental age, gestational age, and other birth characateristics |
| Meta-analysis USA & Canadac 1980–2002 [40] | Valery et al. (2005) | ES 357 | 745 | Hernias |
| Cohort Connecticut, USA 1936–1979 [45] | Tucker et al. (1987) | MBT 64 | 9,170 | Radiotherapy (treatment of primary childhood cancers) |
| Case–control Ontario, Canada 1964–1988 [46] | Finkelstein et al. (1996) | MBT 238 | 432 | Radium in drinking water |
| North Carolina, United States 1967–1976 [47] | Grufferman et al. (1982) | RS 33 | 99 | Parental smoking habits, maternal age, maternal antibiotic use, and vaccination history |
| Northern England 1968–2000 [48] | Pearce et al. (2007) | MBT 245 & STS 320 | 29,520 | Paternal occupational exposure to electro-magnetic fields |
| USA-multiple locations 1972-? [47] | Winn et al. (1992) | ES 208 | 395 | Parental smoking habits, hernias, and parental occupational factors |
| USA 1972–1997 [49] | Grufferman et al. (1993) | RS 322 | 322 | Parental cocaine and marijuana use |
| Los Angeles, USA 1972–1981 [50] | Operskalski et al. (1987) | OS 64 | 124 | Birth length, gestational age and height at diagnosis |
| New York State, USA 1978–1988 [51] | Gelberg et al. (1997) | OS 130 | 130 | Birth weight, birth height, and pubertal growth factors |
| United Kingdom 1980–1983 [52, 53] | Hartley et al. (1988), Hartley et al. (1988) | MBT 30 & STS 43, MBT 30 & STS 43 | 146, 146 | Birth weight, pregnancy conditions, antibiotic use after birth |
| Ontario, Canada 1980–1988 [54] | Hum et al. (1998) | MBT 152 | 713 | Parental occupations |
| USA & Canada 1983–1987 [55] | Buckley et al. (1998) | OS 152 & ES 153 | 305 | Birth weight, birth height, and pubertal growth factors |
| United Kingdom 1991–1996 [56] | Smith et al. (2009) | MBT & STS 251 | 6,337 | Birth weight and gender |
| Austrailia 1991–1996 [57, 58] | Valery et al. (2003), Valery et al. (2002) | ES 106, ES 106 | 344, 344 | Parental occupation, hernias, and pubertal growth factors |
| USA-multIple locations 1992–1995 [59] | Bassin et al. (2006) | 139 | 280 | Fluoride levels in drinking water |
| Germany 1992–1997 [60, 61] | Schuz et al. (2007), Shuz et al. (1999) | MBT 97 & STS 137, MBT 97 & STS 137 | 2057, 2588 | Birth weight, family size, maternal age, gestational age, paternal smoking, birth weight for gestational age, and other birth characateristics |
| USA-multiple locations 1994–2000 [62] | Troisi et al. (2006) | OS 158 | 141 | Birth weight, birth length, birth order, height and weight at diagnosis, and other pubertal growth factors |
| Case-series USA-multiple locations 1972–1978 [63] | Pendergrass et al. (1984) | ES 291 | N/A | Adolescence stature: height and weight |
| United Kingdom 1978–1997 [64] | Cotterill et al. (2004) | MBT 720 | N/A | Adolescent height, stature, and growth factors |
