Table 2 OS Incidence rates, murine genotypes & its associated cell lineages

Mesenchymal / Skeletal progenitors

Prx1-Cre-p53^fl/fl

61% [55]; 62% [56]

Prx1-Cre-p53^fl/fl-Rb^fl/+

92% [56]

Prx1-Cre-p53^fl/fl-Rb^fl/fl

18% [55]; 29% [56]

Pre-Osteoblasts

Osx-Cre-Rb^fl/fl

0% [24]; 0% [25]

Osx-Cre-p53^fl/fl

100% [24]; 100% [25]

Osx-Cre-p53^fl/fl-Rb^fl/fl

53% [24]; 100% [25]

Osx-Cre-p53^fl/fl-Rb^fl/+

72% [24]; 100% [25]

Col1〈13.6-Cre-p53^fl/fl

60% [193]

Osteoblasts

Col1〈12.3-Cre-p53^fl/fl

85% [55]

Osteocalcin-SV40 T antigen

100% [156]