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Table 3 A summary of human BMMSCs transformation without specific chromosomal translocation

From: Mesenchymal stem cell transformation and sarcoma genesis

Type of sarcomas

Expressed gene(s)/treatment

Reference

Undifferentiated spindle cell sarcoma

hTERT + HPV16 E6/E7 + SV40-ST + H-RAS

[44]

hTERT + SV40-LT + H-RAS

[13]

hTERT + H-RAS + BMI-1

[43]

Tumors with smooth muscle and bone properties

hTERT4

[33]

Undifferentiated pleomorphic sarcomas

DKK1 + SV40-LT

[14]

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Clinical Sarcoma Research

ISSN: 2045-3329