Figure 1
From: Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinib
Path evaluation of Patient 1, Hematoxilin and Heosin-stained (H&H) section. Tumor biopsy consistent with the diagnosis of PVNS. Histology shows a tumor characterized by a cleft-like space growth lined by synovial-like cells (panel A, 50x original magnification, red arrow) and a mixed cellular component made-up of mononuclear round small and large discohesive cells (panel B, 100x magnificent magnification, green arrows), rare osteoclast-like giant cells (panel B, violet arrow), inflammatory cells (panel B, blue arrow).