Setting | Dosage |
---|---|
Pre-operative radiotherapy | The total dose for preoperative irradiation is 50.4Â Gy in 28 fractions in a single phase to the PTV. If there are concerns about organ tolerance or wound healing, then this dose can be reduced to 45Â Gy in 25Â Gy fractions |
Post-operative radiotherapy | The total dose for postoperative radiotherapy is 54Â Gy in 30 fractions, delivered as 45Â Gy in 25 fractions to PTV1, and 9Â Gy in 5 fractions to PTV2 |
Definitive radiotherapy | The total dose for definitive radiotherapy is 54Â Gy in 1.8Â Gy fractions, delivered as a single phase. A boost of 5.4Â Gy in 3 fractions may be considered if desired, keeping within standard normal tissue dose constraints |