Table 2 Demographics and clinical characteristics of patients with advanced STS
Characteristic | Total (n = 253) | Treated groupa (n = 86) | Not treated groupb (n = 167) | P |
|---|---|---|---|---|
Age at diagnosis | ||||
Mean (range) | 59 (18–91) | 51 (18–85) | 63 (22–95) | N/A |
Number of patients | ||||
<65 years, n (%) | 147 (58) | 68 (27) | 79 (31) | 0.0001 |
≥65 years, n (%) | 106 (42) | 18 (7) | 88 (35) | |
Gender, n (%) | ||||
Female | 104 (41) | 37 (15) | 67 (26) | 0.687 |
Male | 149 (59) | 49 (19) | 100 (40) | |
Stage IV at diagnosis | 86 (34) | 32 (13) | 51 (20) | 0.323 |
n (%) | ||||
Histological type, n (%) | ||||
UPSc | 57 (23) | 21 (8) | 36 (14) | N/A |
Leiomyosarcoma | 44 (17) | 22 (9) | 22 (9) | |
Liposarcoma | 34 (14) | 9 (4) | 25 (10) | |
Synovial sarcoma | 21 (8) | 15 (6) | 6 (2) | |
Other | 97 (38) | 19 (7) | 78 (31) | |
Sites of metastases, n (%) d | ||||
Lung | 167 (66) | 78 (31) | 89 (35) | N/A |
Intra-abdominal | 70 (28) | 32 (13) | 38 (15) | |
Bone | 48 (19) | 28 (11) | 20 (8) | |
Lymph node | 44 (17) | 16 (6) | 18 (7) | |
Head and neck | 6 (2) | 3 (1) | 3 (1) | |
Other | 27 (11) | 10 (4) | 17 (7) | |