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Table 3 Summary of palliative systemic therapy in treated patients

From: Patterns of care for patients with advanced soft tissue sarcoma: experience from Australian sarcoma services

Systemic therapy line, n (%a)

Treatment details

First-line (n = 86, 100 %)

Single-agent chemtoherapy (n = 62, 72 %)

Doxorubicin (n = 43)

Clinical trial (n = 7)

Ifosfamide (n = 4)

Paclitaxel (n = 3)

Other (n = 5)

Combination therapy (n = 24, 28 %)

Doxorubicinb and ifosfamide (n = 13)

Clinical trial (n = 7)

Other combination (n = 4)

Second-line (n = 38, 44 %)

Single-agent chemtoherapy (n = 35, 92 %)

Ifosfamide (n = 20)

Dacarbazine (n = 5)

Pazopanib (n = 3)

Clinical trial (n = 3)

Other (n = 4)

Combination therapy (n = 3, 8 %)

Third-line (n = 20, 23 %)

Single-agent chemtoherapy (n = 18, 90 %)

Pazopanib (n = 6)

Dacarbazine (n = 6)

Cyclophophamide (n = 3)

Other (n = 3)

Combination therapy (n = 2, 10 %)

Fourth-line (n = 6, 7 %)

Single-agent chemtoherapy (n = 6, 100 %)

Pazopanib (n = 2)

Doxorubicin (n = 1)

Ifosfamide (n = 1)

Cyclophophamide (n = 1)

Trabectedin (n = 1)

Fifth-line (n = 1, 1 %)

Pazopanib (n = 1)

  1. aThe percentage refers to the proportion of patients who received the corresponding line treatment out of the total number treated with systemic therapy (n = 86)
  2. bOne patient had epirubicin and ifosfamide