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Table 2 Modified NIH risk classification for primary GIST

From: UK clinical practice guidelines for the management of gastrointestinal stromal tumours (GIST)

Risk category

Tumour size (cm)

Mitotic index (per 50 HPFs)

Primary tumour site

Very low risk

<2.0

≤5

Any

Low risk

2.1–5.0

≤5

Any

Intermediate risk

2.1–5.0

>5

Gastric

<5.0

6–10

Any

5.1–10.0

≤5

Gastric

High risk

Any

Any

Tumour rupture

>10

Any

Any

>5.0

>5

Any

2.1-5.0

>5

Non gastric

5.1–10.0

≤5

Non gastric

  1. After Joensuu [18]